Jun
14
2008
The US Food and Drug Administration (FDA) has received reports of sudden reduction or loss of hearing following the use of PDE5 inhibitors, a class of drugs
that includes the erectile dysfunction (ED) medications Viagra, Levitra, and Cialis and also Revatio, used to treat pulmonary arterial hypertension
(PAH).
The FDA has approved manufacturers’ label changes for the ED drugs that highlight this risk more prominently and advise consumers what to do if they
experience sudden problems with hearing.
The revised labelling for the ED drugs includes a new Precaution and updated Adverse Reactions Sections. A similar update is expected soon for the PAH drug,
kaufen viagra Ohne Rezept Revatio. PAH is a potentially fatal condition where continuous high blood pressure in the arteries of the lungs weakens heart muscle and can lead to heart
failure and death.
In some cases the sudden loss of hearing is reported to be accompanied by tinnitus (ringing in the ears) and dizziness. The FDA said it is not possible to
establish if the hearing loss and accompanying symptoms are directly caused by the drugs because medical follow up information is limited. It is possible
the symptoms are caused by other drugs or underlying medical conditions, or even other risk factors for hearing loss, or a combination of these
things.
The number of reports of people experiencing sudden hearing loss after taking PDE5 inhibitors is said to be "very small", but there is also concern that some patients,
especially the elderly, may not realise their symptoms could be drug related, said Dr Janet Woodcock, FDA deputy commissioner for scientific and medical
programs, chief medical officer, and acting director of the FDA’s Center for Drug Evaluation and Research:
"Because some level of hearing loss is usually associated with the aging process, patients on these drugs may not think to talk to their doctor about it."
The FDA said that patients who are taking Cialis, Levitra, or Viagra and find themselves suddenly losing the ability to hear, should stop taking them
immediately and go and see their doctor. Patients taking Revatio should not stop taking it because it is treating a potentially life-threatening condition.
Instead they should continue to take the drug but seek medical attention immediately for further evaluation and advice.
The FDA said they were prompted to search its Adverse Events Reporting System for cases of hearing loss with PDE5 inhibitors after reading an
article about a man who experienced these symptoms after taking Viagra that was published in the April 2007 issue of the Journal of Laryngology &
Otology.
The agency found 29 reports of patients experiencing sudden hearing loss (mostly in one ear only) linked with PDE5 inhibitors, with and without
tinnitus, vertigo, or dizziness. In about one third of the cases the loss was temporary.
PDE5 inhibitors relax smooth muscle tissue in the blood vessels of the penis enabling their dilation and increasing blood supply to the corpus cavernosum
which leads to an erection. PDE5 is also present in the smooth muscle in the walls of arteries in the lungs, so PDE5 inhibitors are used to treat high blood
pressure caused by when these arteries become too narrow.
Click here for "Questions and Answers about Viagra, Levitra, Cialis, and
Revatio: Possible Sudden Hearing Loss" (FDA).
Written by: Catharine Paddock
View drug information on Cialis; Levitra; Viagra.
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
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Jun
14
2008
Cook Medical , announced the launch of www.MensHealthPD.com, an informational microsite dedicated to educating physicians, men and their partners about the symptoms, treatment options and latest research on Peyronie’s disease, a common form of erectile dysfunction thought to affect more than 80, 000 men in the UK, with one study suggesting 1% of the male population may suffer. MensHealthPD.com is designed to provide the latest information on the painful ailment and also offers medical professionals, patients and their partners public and physician forums for discussing the disease, posting questions and sharing personal experiences about the condition.
For many men and their partners, erectile dysfunctions, such as Peyronie’s disease, are embarrassing and uncomfortable to discuss. It is also often difficult to find a centralised repository on the web with the helpful information needed to obtain answers on these conditions. MensHealthPD.com is changing all this by offering these individuals a one-stop, discreet Peyronie’s resource armed with the following assets:
- Video answers to the most commonly asked questions about Peyronie’s disease provided by some the world’s leading Peyronie’s doctor experts.
- A Q&A forum where patients, partners and doctors can discuss available Peyronie’s treatments, exchange ideas on coping with the disease and more.
- Details of the signs, symptoms and progression of Peyronie’s disease.
- A helpful list of questions to prepare a man afflicted with Peyronie’s for his first doctor’s visit
comprare il viagra pillole|comprare generico viagra|generico viagra in linea comrare|comprare il viagra senza ricetta|Generico viagra pillole senza ricetta Many men living with Peyronie’s disease go untreated because so few GPs understand the disease. In fact, a recent study showed that over half of primary care physicians were unsure any effective treatments for the disease existed. Therefore, many men never get referred to a urologist who may be able to treat the condition.
MensHealthPD.com will serve as a single source where GPs, urologists and other physicians from around the world can access the latest peer-reviewed research on Peyronie’s treatment options as well as other relevant published scientific data. The following resources are available on the microsite to educate these doctors on the wide array of treatment options available for Peyronie’s sufferers:
- A summary of current surgical and non-surgical treatment options with links to the most current published research.
- The latest peer-reviewed research on Peyronie’s disease posted in the MEDLINE database of citations and abstracts and indexed through PubMed, offered by the US National Library of Medicine and the National Institutes of Health (NIH).
- A secure, physicians-only Q&A forum where doctors can share best practices and increase their collective knowledge with their colleagues.
Raj Persad, a Consultant Urologist at United Bristol Healthcare NHS explains: "This is a distressing disease with huge potential psychosexual impact. In an area such as this where treatment options for different stages of the disease are limited and often confusing for patients we need to share as much information as possible about new management options. This website will benefit both clinicians and patients alike in enabling the sharing of experience and information which could be of benefit to all’
About Peyronie’s Disease
Peyronie’s disease, also known as penile curvature, is estimated to affect nearly four out of every 100 males between the ages 45 and 65[3]. The disease is linked to erectile dysfunction in 20 to 40 percent of the sufferers and is characterised by the formation of a plaque or hardened scar tissue beneath the skin of a man’s penis. The scarring is non-cancerous and may lead to a painful erection and curvature of the penis during erection.
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